CNBP PhD Student Ms Yuan Qi Yeoh enjoyed a two week collaborative visit with Prof Xuefeng Guo’s team at Peking University. Working with Peking University PhD student Xinjiani Chen on a research project involving the molecular dynamics of the secondary structure of a cyclic photoswitchable peptide.
Yuan Qi had the opportunity to participate in the fabrication process of the single-molecule devices. Specifically, they carried out temperature-dependent experiments using their advanced facilities to probe the molecular dynamics of the secondary structure upon photoswitching.
Yuan Qi says that “It was a great opportunity to collaborate with colleagues at Peking University in such high impact research and enjoyed working in their sophisticated research labs”
30 March 2017:
CNBP welcomes its latest PhD candidate Yuan Qi Yeoh who is working on controlling the structure and activity of an antimicrobial peptide using an azobenzene photoswitch.
Supervised by CNBP Chief Investigator Prof Andrew Abell at the University of Adelaide, Yuan Qi will design and synthesise peptides that mimic Gramicidin S, incorporating azobenzene to turn antimicrobial activity on and off when desired.
Tested will be the effectiveness of the synthetic peptidomimetics by biological assays against S. aureus and E. coli – this recognising the structure-activity relationship of the synthetic peptidomimetics against bacteria.
Previously, Yuan Qi completed an Honours Degree at the University of Adelaide under the guidance of Prof Abell with her thesis titled, “Controlling the Conformation of a Modified Gramicidin S Cyclic Peptidomimetic with an Azobenzene Photoswitch.”
She has also participated in summer research (synthesising an azobenzene photoswitch) supervised by both Prof. Andrew Abell and CNBP Research Fellow Dr. Jingxian Yu.
Welcome to the CNBP team Yuan Qi!