Tag Archives: microscopy

Breaking the blur barrier

7 May 2020:

Medical researchers face a hurdle when studying cells under an optical microscope — the laws of physics. Obtaining an image of anything below a certain size is complicated; optical apertures and the wavelength of visible light play havoc with clarity. Known as the diffraction limit, it was first encountered by German physicist Ernst Abbe in 1873, and limits the resolution to 200 nanometres (nm) at best (or 200 billionths of a metre). Continue reading

In hot pursuit

29 April 2020:

A host of diseases – like meningitis, diabetes, cystic fibrosis, Alzheimer’s disease, even some cancers – are ultimately caused by problems at the cellular level. Hence, understanding what is happening inside cells is essential. Observing cells under a microscope helps, but what medical researchers would really like to do is see processes inside cells in minute detail. Continue reading