Tag Archives: Malcolm Purdy

A picture says a 1000 words

Mel McDowall High Res Edit 004001 May 2015 :

A recently published article by Mel Sutton-McDowall and collaborators (Jeremy Thompson, Malcolm Purdey, Ewa Goldys, Hannah Brown and Andrew Abell) has made the front cover of the Molecular Reproduction and Development Journal. The paper examined the influence of an oocyte specific growth factor BMP15  follicle stimulating hormone (FSH) on oocyte metabolism. The study was the result of CNBP cross nodal and transdisciplinary collaboration.

The cover can be found : http://onlinelibrary.wiley.com/doi/10.1002/mrd.22394/abstract;jsessionid=5318322C961EE49865D8E3C683A2E7EE.f01t01

and the paper is available here: http://onlinelibrary.wiley.com/doi/10.1002/mrd.22470/abstract

Advances in Hydrogen Peroxide Sensing Presented in Denver and Prague

Malcolm Purdey Low Res Edit 007521 April 2015:

Hydrogen peroxide plays an important role in reproductive health, and recent work from the University of Adelaide node has looked at different ways of detecting hydrogen peroxide in sperm and embryos. Recent advances in non-invasively monitoring hydrogen peroxide concentrations near developing embryos were presented at two international conferences.

The American Chemical Society (ACS) National Congress is a biannual event which gathered 14,000 Chemists from around the world at the Colorado Convention Center in Denver, CO. This work was presented in the Division of Organic Chemistry in a poster entitled “Hydrogen Peroxide Sensing for Reproductive Health”.

An Optics and Optoelectronics conference is run by SPIE in Prague every second year, with over 700 attendees this year at the Clarion Congress Hotel. A paper entitled “Localised Hydrogen Peroxide Sensing for Reproductive Health” was presented at the Optical Sensors Conference along with a presentation from University of Adelaide researcher Matthew Henderson on localised pH sensing.

Publication: Molecular Reproduction and Development

 

Embryo stained

3 February 2015 – Interdisciplinary and inter-node publication

Accepted in next to no time – CNBP scores our first internode and interdisciplinary Embryo publication

We have just submitted this paper a few days ago and the editor liked it so much that it was immediately accepted!  The paper cited below is a result of joint work between Dr Mel McDowall  and A/Prof Jeremy Thompson with other embryology co-authors, Prof Andrew Abell  and PhD Student Malcolm Purdy  (Chemistry Adelaide node of CNBP), and Prof Ewa Goldys (Physics, MQ node of CNBP). Andrew provided unique reagents and Ewa introduced quantitative analysis of the images. The images are also lovely, and Mel made a nice desktop background which we will submit for the journal cover.

This event demonstrates our collective power when we apply our diverse disciplines to a single CNBP biological challenge.

 “REDOX and anti-oxidant state within cattle oocytes following in vitro maturation with bone morphogenetic protein 15 and follicle stimulating hormone

Melanie L Sutton-McDowall 1,2, 7, Malcolm Purdey 2; Hannah M Brown 1, Andrew Abell 2; David G Mottershead 1, Pablo D Cetica 3, Gabriel C Dalvit 3, Ewa M Goldys 4; Robert B Gilchrist 1, 6, David K Gardner 5 & Jeremy G Thompson 1, 2

Accepted in Molecular Reproduction and Development.  Accepted 3 Feb 2015

 

Publication: New probes for detection of defects in human sperm.

Malcolm Purdey Low Res Edit 007530 January 2015: Free Radical Biology Medicine

New fluorescent molecules for detecting oxidative stress in sperm has just been published by researchers in the Recognise theme at the University of Adelaide. The article in Free Radical Biology and Medicine outlines the use of the compounds in human sperm, and their ability to differentiate between poor and good sperm. It is hoped that these fluorescent probes will aid in the diagnosis of male infertility.

Purdey, Malcolm; Schartner, Erik; Monro, Tanya; Thompson, Jeremy; Abell, Andrew: New molecules for detecting oxidative stress in sperm; Free Radical Biology and Medicine.

Dowload the full article:  http://www.sciencedirect.com/science/article/pii/S0891584915000222#