Monthly Archives: January 2016

IPAS best papers competition

cnbplogosquare129 January 2016:

CNBP researchers featured prominently in the recent ‘Institute for Photonics and Advanced Sensing (IPAS) Best Papers’ competition.

The awards, presented in January 2016,  aim to showcase the quality and impact of the research being conducted by IPAS members.

Winners for the best ECR led Paper were Abel Santos, Agnieszka Zuber and CNBP Research Fellow Xiaozhou (Michelle) Zhang.

The best PhD Student Led Paper Awards went to CNBP student Malcolm Purdey, Parul Mittal and Tess Reynolds.

The Best Transdisciplinary Paper with a Strong Medical/Animal Science Element went to CNBP senior researcher Melanie McDowall.

Full details on the awards, all of the winners and their papers can be found at the IPAS web site.

Counting cancer-busting oxygen molecules

Ewa Goldys Low Res Edit 015928 January 2016:

CNBP researchers have established that a therapeutic dose of X-rays, in combination with CeF3 nanoparticles, can produce enough singlet oxygen molecules to be effective in photodynamic therapy. The finding has been reported in the journal Scientific Reports, published online today.

The complete research paper is available for download, from the Nature Publishing Group web site. A CNBP media release has also been produced.

Jeremy Thompson awarded Commercial Accelerator Grant

Jeremy Thompson27 January 2016:

Adelaide Research and Innovation has awarded A/Prof. Jeremy Thompson (CNBP Chief Investigator at the University of Adelaide) a Commercial Accelerator Grant of $38 000 for novel storage systems of cattle embryo production media.

Thompson notes that, “The cattle in vitro embryo production industry is hamstrung in having a major impact in improving the genetics of animals, by poor performance of generating good quality embryos from the valuable oocytes collected from an individual cow.”

“Amongst the many factors that are involved in making embryos, a major limitation is the performance of the embryo production solutions. These are highly specialised formulations and require sterile/clean room facilities to manufacture, an unbroken cold change for delivery to a specific site and have a short shelf-life of only 4 weeks.”

“We have been developing an alternative packaging system which will remove these barriers. This  was attractive to the CAS grant committee, who awarded $38,800 for the project to start immediately in 2016.”

Further information on successful Adelaide Research and Innovation grants is available online.

Hannah Brown at GYSS

Hannah-Brown22 January 2016:

Hannah Brown, CNBP researcher, has attended the Global Young Scientists Summit@one-north (GYSS) in Singapore, 17-22 January, 2016.

The Summitt, an international gathering of 300 young researchers from all over the world, is a forum where attendees meet for a week to be inspired by internationally eminent science and technology leaders via plenary sessions, panel discussions, small group sessions and site visits.

This year, twenty one distinguished speakers took part in the 2016 event which included – 13 Nobel Laureates, 4 Turing Awardees, 2 Fields Medalists and 2 Millennium Technology Prize Winners.

Discussions were focused on how research and innovation can be harnessed to address major global challenges. The specific topic focus this year – “Sustainable and Liveable Cities.”

Additional information can be found online at the GYSS web site.

 

New CNBP student at Macquarie University

Manoj_3a20 January 2016:

CNBP welcomes its newest student Manoj Kale, who will be undertaking a two year Master of Research program at Macquarie University.

Manoj will be supervised by CNBP Deputy Director Prof. Ewa Goldys as well as joining her research group – the title of his research thesis, “Fluorescence in Biomedicine.”

Prior to enrolling at Macquarie University, Manoj completed a Bachelor of Engineering in Electronics and Telecommunication from the Government College of Engineering, Aurangabad, India.

He then undertook a Master of Technology in Nanotechnology at the Vellore Institute of Technology, Vellore, India, achieving expertise in nanomaterial synthesis and characterization techniques.

His career goal is to join a research-oriented organisation and to continue to further his research in novel nanomaterials synthesis and application in the field of Biophysics and Biophotonics.

Welcome to the team Manoj!

 

Supporting Science Experience 2016

Varun Sreenivasan_web15 January 2016:

CNBP researchers  Varun Sreenivasan and Denitza Denkova extended their outreach skills in support of the ConocoPhillips Science Experience program that took place at Macquarie University 13-15th January 2016.

The national program, focused on  Year 9 and 10 students who have an interest in science, is rolled-out across universities and tertiary institutions across Australia. Students who attend are provided with the opportunity to engage in a wide range of fascinating science activities under the guidance of scientists who love their work.

As a part of this program, Varun and Denitza contributed to the ‘Physics and Chemistry Magic Show’ which ran for an hour at Macquarie University’s Science Faculty. Demonstrated were concepts such as the ‘Stroboscopic effect’, the physics behind a ‘singing wineglass’ and the fun that can be had with Sulfur Hexafluoride.

“Through this event, we were able to share our excitement of science with youngsters, hopefully motivating them to do science as they grow up,”said Varun.

“We also improved our presentations and quick problem solving skills too!”

 

Cytokine detection based on immunosensing

guozhen_liu8 January 2016:

CNBP researchers Guozhen Liu, Mark Hutchinson and Ewa Goldys are all authors on a recent review paper examining the detection of cytokines  based on immunosensing. The paper was published in the journal Biosensors and Bioelectronics.

Paper Title:  “Recent advances in cytokine detection by immunosensing.”

Abstract: The detection of cytokines in body fluids, cells, tissues and organisms continues to attract considerable attention due to the importance of these key cell signaling molecules in biology and medicine. In this review, we describe recent advances in cytokine detection in the course of ongoing pursuit of new analytical approaches for these trace analytes with specific focus on immunosensing.

We discuss recent elegant designs of sensing interface with improved performance with respect to sensitivity, selectivity, stability, simplicity, and the absence of sample matrix effects. Various immunosensing approaches based on multifunctional nanomaterials open novel opportunities for ultrasensitive detection of cytokines in body fluids in vitro and in vivo.

Methodologies such as suspension arrays also known as bead assays together with optical fiber-based sensors, on their own or in combination with microfluidic devices will continue to have an important role to address the grand challenge of real-time in vivo multiplex cytokine detection.

The paper is available online.

 

Ground breaking hybrid nanocrystal work

Dayong Jin  Low Res Edit 00968 January 2016:

The top ranking journal ‘Nature Communications’ has published the latest ground breaking research from CNBP scientists with a paper titled, ‘Three-dimensional controlled growth of monodisperse sub-50 nm heterogeneous nanocrystals’.

The paper details the creation of  a library of over 800 newly shaped nanocrystals formed from ordered atom clusters over a period of three years. The different shaped or ‘hybrid’ nanocrystals will act as new tools impacting the areas of bio-imaging, diagnostics and nano-medicine.

According to CNBP Chief Investigator, Prof Dayong Jin, the work could form new solutions to getting around the body’s immune system response in the targeted treatment of cancerous cells, which causes both the healthy and diseased cells to die.

The full text of the paper is available online from the Nature Communicatons web site.